Myopathy with Concurrent Tadalafil and Simvastatin

Myopathy with Concurrent Tadalafil and Simvastatin

Blog Article

A 48-year-old man, using statin, was admitted to hospital with progressive myalgia after consumption of tadalafil and simvastatin.Muscle pain u11-200ps and penile erection disappeared seven days after interruption of therapy.This case demonstrates the interaction of tadalafil with simvastatin resulting in myopathy.Muscle damage could be attributed to the common weboost splitter metabolic way of these two drugs which is cytochrome P450 isoenzyme system.